Prognostic factors in nonmetastatic, favorable histology wilms' tumor. Results of the third national wilms' tumor study
نویسندگان
چکیده
منابع مشابه
Treatment of Wilms' tumor. Results of the Third National Wilms' Tumor Study.
The Third National Wilms' Tumor Study sought to reduce treatment for low-risk patients and find better chemotherapy for those at high risk for relapse. Eligible patients (1439) were randomized according to stage (I-IV) and histology (favorable [FH] or unfavorable [UH]), and contributed data to survival and relapse-free survival (RFS) analyses. Four-year (postnephrectomy) survival percentages an...
متن کاملOutcome of patients with Stage II/favorable histology Wilms tumor with and without local tumor spill: a report from the National Wilms Tumor Study Group.
BACKGROUND Intra-operative tumor spill increases the risk of local recurrence of Wilms tumor, and adversely impacts relapse-free (RFS) and overall survival (OS) rates. METHODS Surgical checklists, operative notes, institutional pathology reports, central pathology review and flow sheets of 602 patients registered between August 1986 and September 1994 on National Wilms Tumor Study-4 as random...
متن کاملEvaluation of CD133 and CD56/NCAM expression in Wilms tumor and their association with prognostic factors
Objective(s): To validate certain markers for cancer stem cell populations and their clinical importance in Wilms tumor (WT)Materials and Methods: Immunohistochemical study for CD133 and CD56/NCAM was performed on forty-six cases of WT that were diagnosed between 1999 and 2015, and the association of these markers with survival and progn...
متن کاملIntraoperative spillage of favorable histology wilms tumor cells: influence of irradiation and chemotherapy regimens on abdominal recurrence. A report from the National Wilms Tumor Study Group.
PURPOSE We undertook this study to determine (1) the frequency with which spilled tumor cells of favorable histology produced intra-abdominal disease in patients treated with differing chemotherapy regimens and abdominal radiation therapy (RT) and (2) the patterns of relapse and outcomes in such patients. METHODS AND MATERIALS The influence of RT dose (0, 10, and 20 Gy), RT fields (flank, who...
متن کاملThe management of synchronous bilateral Wilms tumor: a report from the National Wilms Tumor Study Group.
OBJECTIVE To provide guidelines for future trials, we reviewed the outcomes of children with synchronous bilateral Wilms tumors (BWT) treated on National Wilms Tumor Study-4 (NWTS-4). METHODS NWTS-4 enrolled 3335 patients including 188 patients with BWT (5.6%). Treatment and outcome data were collected. RESULTS Among 188 BWT patients registered with NWTS-4, 195 kidneys in 123 patients had i...
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ژورنال
عنوان ژورنال: Cancer
سال: 1991
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19911201)68:11<2345::aid-cncr2820681103>3.0.co;2-t